Research Field
We are working on several ideas and areas — from arsenic-induced epigenetic alterations to metabolic disease mechanisms.
Areas of Investigation
Each project bridges molecular biology, environmental exposure, and human health.
Arsenic Toxicity targeting Telomere Epigenetics
Investigating how chronic arsenic exposure alters telomere length dynamics and epigenetic marks, contributing to accelerated cellular aging. The study focuses on DNA methylation changes at telomeric regions, histone modifications, and their cumulative impact on cellular senescence in arsenic-exposed populations of West Bengal.
Different Signalling Pathways in Chronic Kidney Disease and therapeutic implications
Decoding dysregulated molecular signalling cascades in Chronic Kidney Disease (CKD) progression and identifying druggable targets for intervention. This research integrates transcriptomic profiling, pathway enrichment analysis, and in silico modelling to pinpoint key nodes in fibrosis and inflammation.
Epigenetic Modification in Renal Inflammation and Fibrosis by Arsenic; Potential Bioactive Compound Based Interventions
Exploring arsenic-induced epigenetic reprogramming in renal inflammation and fibrosis, and evaluating bioactive compounds as potential therapeutic interventions. The work combines in vitro cell models, in vivo exposure studies, and phytochemical screening to identify novel epigenetic modulators.
Epigenetic alterations in Obesity & related metabolic diseases
Unravelling DNA methylation, histone modification, and miRNA-based mechanisms underlying obesity and metabolic syndrome. The research examines how environmental exposures and lifestyle factors translate into stable epigenetic marks associated with insulin resistance, adipogenesis, and systemic inflammation.
Our Research Approach
Sample Collection
Field surveys and clinical sample gathering from exposed populations.
Molecular Analysis
DNA methylation, histone modification, and gene expression profiling.
Data Modelling
Statistical and mathematical modelling to identify biomarkers.
Intervention Design
Translating findings into therapeutic and preventive strategies.
Interested in collaborating on a research project?
We welcome interdisciplinary partnerships and student researchers.
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